Located in the heart of Westlake within the vibrant Rampart Village community, this classic 1921 duplex at 221 S Reno St presents a rare opportunity for both investors and owner-users seeking strong rental demand and central city access. Offering 3,136 sqft of living space on a 4,806 sqft lot, this well-maintained property features two spacious units, each with 2 bedrooms and 1 bathroom, totaling 4 bedrooms and 2 baths. The upper unit (221 S Reno St) and lower unit (223 S Reno St) provide functional and flexible layouts ideal for multi-generational living or rental income. The property retains its original character while offering practical living spaces. While there is no garage, the property includes rear alley access with parking, a valuable feature in this high-demand urban setting. Positioned just minutes from MacArthur Park and Echo Park Lake, residents enjoy nearby green spaces, recreation, and a lively neighborhood atmosphere. The property is also close to major entertainment and employment hubs including Crypto.com Arena and LA Live. Commuting is effortless with convenient access to the Hollywood Freeway (US-101), Santa Monica Freeway (I-10), and Harbor Freeway (I-110), connecting you to all parts of Los Angeles. Daily essentials and dining are just moments away, including the iconic Langer's Delicatessen-Restaurant, along with nearby shopping at Target and Smart & Final. Nearby institutions such as PIH Health Good Samaritan Hospital and UCLA Community School further enhance the property's long-term rental appeal. Centrally located near Downtown LA, Koreatown, and just minutes from Mid-Wilshire, this duplex is ideally positioned for convenience, accessibility, and strong upside potential. Whether you're looking to expand your portfolio or occupy one unit while generating income from the other, this is a standout opportunity in one of LA's most connected rental corridors.